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4-Amino 6 Chloro Benzene 1, 3 Disulfonamide

CAS No. 121 – 30 - 2
Chemical Name 4-AMINO 6 CHLORO BENZENE 1, 3 DISULFONAMIDE
Non propriety Names MCADS, Meta chloro aniline disulfonamide
Molecular Formula C6H8CIN3O4S2
Molecular Weight 285.73

Product Specification

Physical Appearance White to off white crystalline powder
L.O.D. (At 1050C for 3 Hrs.) NMT 0.5 % w/w
Sulphated ash NMT 0.2 % w/w
Clarity and colour of solution 10 % w/v in dimethyl formamide must be clear and slightly yellow
Related substance by TLC Individual impurity  
NMT 0.5% w/v
Total impurities
NMT 2.0 %
It is used as an intermediate for the following drugs :-
Cyclopenthiazide (CAS No 742-20-1)
Cyclothiazide (CAS No 2259-96-3)
Epitizide (CAS No 1764-85-8)
Methyclothiazide (CAS No 135-07-9)
Hydrochlorothiazide Chlorothiazide and many other Diuretic

Therapeutic Category of these Drugs :- Diuretic, Antihypertensive