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Glimepiride Sulfonamide

CAS No. 119018-29-0
Chemical Name N-{2-[4-(aminosulfonyl)phenyl]ethyl}-3-ethyl-4methyl-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide
Non propriety Names Sulfonamide for Glimepiride Pure
Molecular Formula C16H21N3O4S
Molecular Weight 351.4218

Product Specification

Description : Off-white to white, light yellow crystalline powder
Solubility : 1.0 gm in 30 ml Dimeethylformamide - clear solution
Identification by IR
(Optional - only before
dispatch, if specified by party)
: IR spectrum should match with that of standard spectrum
Melting Point : 178 0 C – 188 0 C
Water Content (by KF) : NMT 0.5 % w/w
Chromatographic Purity
(by HPLC)
Impurity at RRT 1.05
Impurity at RRT 1.5
: Purity NLT 99%

 NMT 0.2 % individually
Residual Solvents (By GC) : Methanol NMT 3000 ppm
  Toluence NMT 890 ppm
Particle size by sieve analysis
(Prov.specifications newly added)
: 100 % passing in 200 mesh ASTM / B.S.S.
It is used as an intermediate for the following drug :-
Glimepiride (CAS No 93479-97-1)
Therapeutic Cat. Of This Drug :- Antidiabetic