Glibenclamide Sulfonamide
| CAS No. | 16673-34-00 |
| Chemical Name | 5-chloro-2-methoxy-n- [2-(4sulfamoylphenyl) Ethyl]benzamide |
| Non propriety Names | EBSA, Sulfonamide for Glibenclamide Pure |
| Molecular Formula | C16H17ClN2O4S |
| Molecular Weight | 368.83518 |
Product Specification
| Description | : White to yellowish crystalline powder |
| Melting Range | : 2110C – 2160C |
| Appearance of Solution | : 2.5 % solution in DMF is clear without any deposits |
| Chloride | : NMT 0.2 % |
| L.O.D. | : NMT 1.0 % |
| Assay By UV Spectrophotometer |
: 96.5 to 102.5 % w/w on Dried Basis |
| Related Substance TLC method by HPLC (for USV LTD only) |
: 1) Ortho Isometer NMT 1 % 2) Meta Isometer NMT 2 % 3) Other imp. NMT 2 % 4) Total imp. NMT 5 % Optional : only to be tested befor USV dipatch |
| HPLC (by Aventis method) |
:By product single 0.5% impurity at 1.22<- 0.5% Sum of all byproducts <-1.0% Optional - Only to be tested before Aventis dispatch |
| It is used as an intermediate for the following drug :-
Glibenclamide (CAS No 10238-21-8) Therapeutic Cat. Of This Drug :- Antidiabetic |
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